Formulation and evaluation of nano-ethogel of silver sulfadiazine for treatment of topical burns
نویسندگان
چکیده
The present study deals with the formulation of ethosomal suspension containing silver sulfadiazine, followed by its incorporation into a hydrogel, leading to novel vesicular nano-ethogel sulfadiazine for treatment topical burns. Silver Sulfadiazine ethosomes were prepared hot method suggested Elka Touitou. This was loaded hydrogel made Carbopol 934 in ratio 1:1. chosen as gelling agent it do not cause any sort skin irritation. nanoethosomal formulations SSD evaluated their physical appearance, pH, spreadability, viscosity, extrudability, drug content. In vitro release studies performed five hours and observed that F4 had maximum amount released within duration i.e. 76.80%. complete wrap up this approach incorporated provides an advance sustained targeted delivery sulfadiazine.
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15 صفحه اولFormulation and In Vitro Evaluation of Silver Sulfadiazine Spray
In order to improve local therapeutic techniques for the massively burnt patients and to minimize the pain associated with dressing change, the concept of topical film was utilized to formulate a topical antimicrobial spray. The commonly used topical antimicrobial silver sulfadiazine spray was formulated as a new drug delivery system. The release of therapeutic agents in vitro from medicated sp...
متن کاملFormulation and In Vitro Evaluation of Silver Sulfadiazine Spray
In order to improve local therapeutic techniques for the massively burnt patients and to minimize the pain associated with dressing change, the concept of topical film was utilized to formulate a topical antimicrobial spray. The commonly used topical antimicrobial silver sulfadiazine spray was formulated as a new drug delivery system. The release of therapeutic agents in vitro from medicated sp...
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ژورنال
عنوان ژورنال: IP international journal of comprehensive and advanced pharmacology
سال: 2023
ISSN: ['2456-9542', '2581-5555']
DOI: https://doi.org/10.18231/j.ijcaap.2022.038